Certainly, make the hash values be references to arrays. We call that a HoA.

my %hoa = (
    alpha   => ['A' .. 'Z','a' .. 'z'],
    numeric => [0 .. 9],
);
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You can get at the array elements with multiple indexing: my $char = $hoa{'alpha'}[42]; See perldsc and perllol for more on perl's deeper data structures.