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<P>If I understand your problem correctly, you wish to do curve fitting in PERL using large ammounts of data and then detect excepts that are identified. Yes, there are a number of statistical methods to accomplish that (which I know very little about).
<UL>
<li>The statistical modules for PERL might help. Check them out <a href="http://www.perl.com/CPAN/modules/by-module/Statistics/">here</a>. (or try the Math modules <a href="http://www.perl.com/CPAN/modules/by-module/Math/">here</a>).
<li>I know there is a book that talks about specific curve fitting examples. Ah, <a href="http://www.oreilly.com/catalog/maperl/toc.html">here</a> it is. I believe if you know the math behind the subject, then you can create your own algorithm with the help of this book (and contribute to CPAN!).
<li>May be you don't have to do the curve fitting in PERL. You could use a statistics package for that if there is one that you use and have code/scripts already written for. PERL can be your data parsing and results presentation system and coordinate the work of the curve fitting program.
</ul>
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