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Re: BioInformatics - polyA tail search

by halley (Prior)
on Sep 02, 2003 at 18:54 UTC ( #288387=note: print w/replies, xml ) Need Help??

in reply to BioInformatics - polyA tail search

Does a single file have a single sequence? You said these polyA tails are at (or near?) the end.

If the files have just one sequence and are small enough to fit in memory, slurp into a scalar, strip any irrelevant characters, and the regular expression qr/[AN]{10,}/ would find the tails.

If the files are too large, or have more than one sequence, you'll have to work a little harder to fit in memory. Reading a couple lines at a time, searching the tailing line(s) for a matching tail.

[ e d @ h a l l e y . c c ]

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