Thanks for the reply and benchmark insights. What OS are you running? Running your benchmark on my laptop with macOS 12.1 with perl 5.34 I get similar percentage differences to my original benchmark code:

           
macOS 12.1, your benchmark code:
               Rate methodic   blessy   direct
methodic 16445180/s       --     -27%     -35%
blessy   22503930/s      37%       --     -11%
direct   25252404/s      54%      12%       --


macOS 12.1, rerun of my original benchmark code:

              Rate  method blessed     sub
method  17857143/s      --    -35%    -44%
blessed 27397260/s     53%      --    -14%
sub     31746032/s     78%     16%      --
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