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( [id://3333]=superdoc: print w/replies, xml ) | Need Help?? |
Hi, I'm processing the text below, trying to extract all mentions of chromosomal bands (they're the ones with the numbers and p's and q's). Using this code:
The print statement yields:
Two questions: why doesn't the splice statement get rid of the "52" and "15" elements? Why do none of the dots or hyphens appear for the captured elements? Whole-genome scan studies recently identified a locus on Xq27-q28 Xq11-q12 22q12.1 1q42.2-q43 19q 17p11 1q25 13q12.3 11p11.2 10q25 10q23.31 8p22 8p22 7q11.23 7p22 chromosome segments 19q12-q13.11 linked to prostate tumor aggressiveness by use of the Gleason score as a quantitative trait. We have now completed finer-scale linkage mapping across this region that confirmed and narrowed the candidate region to 2 cM, with a peak between markers D19S875 and D19S433. We also performed allelic imbalance (AI) studies across this region in primary prostate tumors from 52 patients unselected for family history or disease status. A high level of AI was observed, with the highest rates at markers D19S875 (56%) and D19S433 (60%). Furthermore, these two markers defined a smallest common region of AI of 0.8 Mb, with 15 (29%) prostate tumors displaying interstitial AI involving one or both markers. In addition, we noted a positive association between AI at marker D19S875 and extension of tumor beyond the margin (P = 0.02) as well as a higher Gleason score (P = 0.06). These data provide strong evidence that we have mapped a prostate tumor aggressiveness locus to chromosome segments 19q12-q13.11 that may play a role in both familial and non-familial forms of prostate cancer. In reply to regexp and substitute operator problem by dannoura
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