You may may interested in some shared memory, in that case where you can store this variable that you want to change. Try IPC::Shareable
or an equivalent Win32 module in congruence with an intelligent semaphore or mutex lock system. If you're interested in speed, you'll be glad to hear that shared memory is the fastest form of IPC available.
You may also try a pseudo client-server architecture by grabbing info on pipes. In that case, the address is irrelevant (as it should be) and you an copy the info in the pipe's buffer directly to the variable that you wanted to alter "remotely". Then you can close the pipe or wait for another "change value" instruction.
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