To make bigWig files easier to generate, HOMER includes a program creatively named "makeBigWig.pl" that automates all of the steps below.

makeBigWig.pl <tag directory> <genome> [special options] [makeUCSC file options] -webDir /path-to-web-fold/ -url http://webserverURL/bigwigFold/
i.e. makeBigWig.pl PU.1-ChIP-Seq/ mm9  -webDir /var/www/bigWigs/ -url http://ChuckNorrisU.edu/bigWigs/