package New_Config;
use Config;

my $new = tied %Config;

$new->{make} = 'dmake';
$new->{byteorder} = '43215678';
# Specify as many as you like
1;

##</code><code>##

C:\>perl -V:byteorder
byteorder='12345678';

C:\>perl -MNew_Config -V:byteorder
byteorder='43215678';

C:\>perl -V:make
make='gmake';

C:\>perl -MNew_Config -V:make
make='dmake';