@res = (
    {
      solvent => 'h2o',
      F001    => 1.2,
      F101    => 3.2,
      ...
    },
    {
      solvent => 'acetonitrile',
      F001    => 2.2,
      F101    => 7.2,
      ...
    },
    ...
);

##</code><code>##

$res{'h20'}[0]{F001}= 2.2;
...