http.conf:
HTTPD='/usr/sbin/httpd  -X  -DPERLDB -f ~/debug.d/simple.conf'


simple.conf:
     PerlModule ModPerl::PerlRun
      <IfDefine PERLDB>
        PerlRequire ~/handlers/db.pl
      </IfDefine>

  <Location />
         SetHandler perl-script
         PerlHandler ModPerl::PerlRun
         <IfDefine PERLDB>
                 PerlFixupHandler Apache::DB
         </IfDefine>
         Options +ExecCGI
         PerlSendHeader On
         PerlSetupEnv On
    Order allow,deny
    Allow from all
  </Location>


~/handlers/db.pl:
                   use APR::Pool();
                   use Apache::DB ();
                   Apache::DB->init();