use warnings; use strict; use Inline C => Config => BUILD_NOISY => 1; use Inline C => <<'EOC'; void to_FH(FILE * stream) { fprintf(stream, "hello"); fflush(stream); } EOC my ($got1, $got2); $got1 = get_string_1(); chomp($got1); # just in case ... print "OK 1\n" if $got1 eq "hello"; $got2 = get_string_2(); chomp($got2); # just in case ... print "OK 2\n" if $got2 eq "hello"; sub get_string_1 { # Write to a temporary file open TEMPFILE, '+>', undef or die $!; to_FH(*TEMPFILE); seek TEMPFILE, 0, 0; my $ret = ; close TEMPFILE; return $ret; } sub get_string_2 { # Write to a memory file my $out; open MEM, '+>', \$out or die $!; to_FH(*MEM); #close MEM; # Makes no difference return $out; # returns undef ... why ? } __END__ For me, outputs: OK 1 Use of uninitialized value $got2 in scalar chomp at try.pl line 24. Use of uninitialized value $got2 in string eq at try.pl line 25. #### void to_FH(PerlIO * stream) { FILE * stdio_stream = PerlIO_exportFILE(stream, NULL); fprintf(stdio_stream, "hello"); fflush(stdio_stream); PerlIO_releaseFILE(stream, stdio_stream); }