open (my $XML, "-|", "e:\\path\\to\\pdftohtml.exe -xml -zoom 1.4 -stdout $PDF_FILE") or die "pdftohtml failed:\n$!\n$^E";

my $t = XML::Twig->new(
    twig_handlers => {
        '/pdf2html/pagetext[(@top >= 180 and @top <= 190) and (@left >= 100 and @left <= 111)]' => \&RouteTo,
        '/pdf2html/pagetext[(@top >= 215 and @top <= 225) and (@left >= 260 and @left <= 270)]' => \&InvoiceSort,
        '/pdf2html/page' => sub { $_[0]->purge; 1; }, # free memory after every page
    },
    comments   => 'drop',  # remove any comments
    empty_tags => 'normal',# empty tags = <tag/>
);

$t->parse($XML);

close $XML;