my $fields = $perl->{issues}[0]{fields};
# Now you can get
my $customfield_22181     = $fields->{customfield_22181}; # Should get you the desired 'Jira Testing'
my $customfield_11150_val = $fields->{customfield_11150}{value}; # Should be  'Yes' 
my @weekdays              = map {$_->{value}} @{ $fields->{customfield_11780} };