#!usr/bin/perl
use warnings;
use strict;
$|=1;

my $line = '1925,47365,2,650187016,1,1,"MADE FOR DRAWDOWNS, NEVER P/U",16,IFC 8112NP,Standalone-6,,,44,10/22/2015,91607,,B24W02651,,"PA-3, PURE",4/28/2015,1,0,,1,MAN,,CUST,,CUSTOM MATCH,0,TRUE,TRUE,O,C48A0D001EF449E3AB97F0B98C811B1B,POS.MISTINT.V0000.UP.Q,PROD_SMISA_BK,414D512050524F445F504F5331393235906F28561D2F0020,10/22/2015 9:29,10/22/2015 9:30';

my $i=0;
my $line2 = join '', grep { $i++ % 2 ? {s/,/ /g} : 1} split /"/,$line;

print "line 1=$line\n";
print "line 2=$line2\n";

__END__
Odd number of elements in anonymous hash at C:\Projects_Perl\handledoublequotecsv.pl line 9.
Odd number of elements in anonymous hash at C:\Projects_Perl\handledoublequotecsv.pl line 9.
line 1=1925,47365,2,650187016,1,1,"MADE FOR DRAWDOWNS, NEVER P/U",16,IFC 8112NP,Standalone-6,,,44,10/22/2015,91607,,B24W02651,,"PA-3, PURE",4/28/2015,1,0,,1,MAN,,CUST,,CUSTOM MATCH,0,TRUE,TRUE,O,C48A0D001EF449E3AB97F0B98C811B1B,POS.MISTINT.V0000.UP.Q,PROD_SMISA_BK,414D512050524F445F504F5331393235906F28561D2F0020,10/22/2015 9:29,10/22/2015 9:30
line 2=1925,47365,2,650187016,1,1,MADE FOR DRAWDOWNS  NEVER P/U,16,IFC 8112NP,Standalone-6,,,44,10/22/2015,91607,,B24W02651,,PA-3  PURE,4/28/2015,1,0,,1,MAN,,CUST,,CUSTOM MATCH,0,TRUE,TRUE,O,C48A0D001EF449E3AB97F0B98C811B1B,POS.MISTINT.V0000.UP.Q,PROD_SMISA_BK,414D512050524F445F504F5331393235906F28561D2F0020,10/22/2015 9:29,10/22/2015 9:30

##</code><code>##

#!usr/bin/perl
use warnings;
use strict;
$|=1;

my $line = '1925,47365,2,650187016,1,1,"MADE FOR DRAWDOWNS, NEVER P/U",16,IFC 8112NP,Standalone-6,,,44,10/22/2015,91607,,B24W02651,,"PA-3, PURE",4/28/2015,1,0,,1,MAN,,CUST,,CUSTOM MATCH,0,TRUE,TRUE,O,C48A0D001EF449E3AB97F0B98C811B1B,POS.MISTINT.V0000.UP.Q,PROD_SMISA_BK,414D512050524F445F504F5331393235906F28561D2F0020,10/22/2015 9:29,10/22/2015 9:30';

my $i=0;
my $line2 = join '', grep { $i++ % 2 ? {s/,/ /g} : 1} split /"/,$line;


print "line 1=$line\n";
print "line 2=$line2\n";

my $j=0;    # recoded into a slightly different way...
my @csv;
foreach (split /"/,$line)
{
   s/,/ /g if $j++ % 2;
   push @csv, $_;
}
print "\n\n$line\n";
print @csv,"\n";
__END__
first version, 2 warnings....
Odd number of elements in anonymous hash at C:\Projects_Perl\handledoublequotecsv.pl line 9.
Odd number of elements in anonymous hash at C:\Projects_Perl\handledoublequotecsv.pl line 9.
line 1=1925,47365,2,650187016,1,1,"MADE FOR DRAWDOWNS, NEVER P/U",16,IFC 8112NP,Standalone-6,,,44,10/22/2015,91607,,B24W02651,,"PA-3, PURE",4/28/2015,1,0,,1,MAN,,CUST,,CUSTOM MATCH,0,TRUE,TRUE,O,C48A0D001EF449E3AB97F0B98C811B1B,POS.MISTINT.V0000.UP.Q,PROD_SMISA_BK,414D512050524F445F504F5331393235906F28561D2F0020,10/22/2015 9:29,10/22/2015 9:30
line 2=1925,47365,2,650187016,1,1,MADE FOR DRAWDOWNS  NEVER P/U,16,IFC 8112NP,Standalone-6,,,44,10/22/2015,91607,,B24W02651,,PA-3  PURE,4/28/2015,1,0,,1,MAN,,CUST,,CUSTOM MATCH,0,TRUE,TRUE,O,C48A0D001EF449E3AB97F0B98C811B1B,POS.MISTINT.V0000.UP.Q,PROD_SMISA_BK,414D512050524F445F504F5331393235906F28561D2F0020,10/22/2015 9:29,10/22/2015 9:30

2nd version no warnings....
1925,47365,2,650187016,1,1,"MADE FOR DRAWDOWNS, NEVER P/U",16,IFC 8112NP,Standalone-6,,,44,10/22/2015,91607,,B24W02651,,"PA-3, PURE",4/28/2015,1,0,,1,MAN,,CUST,,CUSTOM MATCH,0,TRUE,TRUE,O,C48A0D001EF449E3AB97F0B98C811B1B,POS.MISTINT.V0000.UP.Q,PROD_SMISA_BK,414D512050524F445F504F5331393235906F28561D2F0020,10/22/2015 9:29,10/22/2015 9:30
1925,47365,2,650187016,1,1,MADE FOR DRAWDOWNS  NEVER P/U,16,IFC 8112NP,Standalone-6,,,44,10/22/2015,91607,,B24W02651,,PA-3  PURE,4/28/2015,1,0,,1,MAN,,CUST,,CUSTOM MATCH,0,TRUE,TRUE,O,C48A0D001EF449E3AB97F0B98C811B1B,POS.MISTINT.V0000.UP.Q,PROD_SMISA_BK,414D512050524F445F504F5331393235906F28561D2F0020,10/22/2015 9:29,10/22/2015 9:30

Process completed successfully