RewriteEngine On
RewriteCond %{REQUEST_URI} !^/?script/myapp_fastcgi.pl
RewriteRule ^(.*)$ script/myapp_fastcgi.pl/$1 [PT,L]

##</code><code>##

AH01215: STDIN is not a socket: specify a listen location at /usr/local/share/perl5/Plack/Handler/FCGI.pm line 57.: /home/mydomain/public_html/script/myapp_fastcgi.pl