while (<DATA>) {
    m/Originated From:\s+(.+?)\s+Last Modified/ and print  $1, $/;
}

__END__
Originated From: C:/My Documents/e3001cert_i_2000_707_11a_aft.f06    Last Modified / Created: 08/03/2002
Originated From: D:/My Documents/e3001cert_i_2000_707_11a_aft.f06    Last Modified / Created: 08/03/2002
Originated From: F:/My Documents/e3001cert_i_2000_707_11a_aft.f06    Last Modified / Created: 08/03/2002