my @ips_to_ignore = qw(
192.168.188.3
192.168.11.141
192.168.140.110
);

my $ignore = join "|",map(qr(\Q$_\E),@ips_to_ignore);
$ignore = qr[^(?:$ignore)$];

while (<DATA>){
   chomp;
   print if ($_ !~ /$ignore/);
}


__DATA__
192.168.188.3
192.168.11.141
192.168.140.110
192.168.188.33
192.168.187.12

---output:
192.168.188.33
192.168.187.12