$sql = "select colnm from tblnm where colmn in (?,?,?);
$st = $dbh->prepare($sql);

# Select where colmn in (1, 2, 3)
$st->execute(1, 2, 3);

....

# Select where colmn in (4, 5, 6)
$st->execute(4, 5, 6);