use OLE;
use Win32::OLE::Const 'Microsoft Word';
my $const=Win32::OLE::Const->Load("Microsoft Word 9.0 Object Library");
$word=GetObject OLE("Word.Application");

$word->Selection->HomeKey({unit=>$const->{'wdStory'}});
$word->Selection->Find->{'Text'}='<it></it>';
$word->Selection->Find->Replacement->{'Text'}='';
$word->Selection->Find->Execute({Replace=>$const->{'wdReplaceAll'}});

$word->Selection->HomeKey({unit=>$const->{'wdStory'}});
$word->Selection->Find->{'Text'}='<Title>';
$word->Selection->Find->Replacement->{'Text'}='';
$word->Selection->Find->{'Style'}='Normal';
$word->Selection->Find->Replacement->{'Style'}='Title';
$word->Selection->Find->Execute({Replace=>$const->{'wdReplaceAll'}});