use strict;
my $html;
open( HTML, "<", "some.html" ); # let's suppose the data is in this file
{
local $/;
$html = ; #read all the html data into one string
}
# if you expect just one match (or only want the first one):
my ( $match ) = ( $html =~ /Marker 1(.*?)Marker 2/s );
# alternatively, if there are two or more and you want them all:
my @matches = ( $html =~ /Marker 1(.*?)Marker 2/gs );