C:\test>perl -MDigest::MD5=md5_hex 
-wle"print md5_hex( do{local $/; <> } )" 1Mx4096.db
22502b12bc292ae0a0aa1f4a33942662

C:\test>perl -MDigest::MD5=md5_hex 
-wle"open I, '<:raw', $ARGV[ 0 ]; print md5_hex(do{local $/; <I>})" 1Mx4096.db
66bff1dfd44db7d4402171056d494b2d

C:\test>md5sum 1Mx4096.db
66bff1dfd44db7d4402171056d494b2d *1Mx4096.db