use strict;
use DBI;
use XML::XPath
use XML::XPath::XMLParser;

my $dbh = DBI->connect ("DBI:mysql:database",
                           "root", "password",
                           { RaiseError => 1, PrintError => 0});
my $xp = XML::XPath->new (filename => "input_file.xml");
my $nodelist = $xp->find ('//row');
foreach my $row ($nodelist->get_nodelist ())
   {
   $dbh->do  ("INSERT INTO users1 ( create_string, username)  VALUES (?, ?)",
                undef, # no need for \%attr
                $row->find ("CreateDate")->string_value () =~ s/(\d\d\d\d-\d\d-\d\d)T(\d\d:\d\d:\d\d).*00/$1 $2/g,
                $row->find ("UserName")->string_value ());
   }
$dbh->disconnect ()

##</code><code>##

Sample data
<USERS1>
  <row>
    <CreateDate>2008-03-17T13:31:14.345-07:00</CreateDate>
    <UserName>foo</UserName>
    <Email>michael@example.com</Email>
    <UserId>a58d0b09-4f97-42ef-901e-cee41103bc12</UserId>
  </row>
  <row>
    <CreateDate>2008-04-11T14:59:57.123-07:00</CreateDate>
    <UserName>bar</UserName>
    <Email>spot@example.com</Email>
    <UserId>4b618e05-1eca-494b-baa5-ab85bd46f0f3</UserId>
  </row>
</USERS1>

##</code><code>##

create_table_users1.sql
CREATE TABLE users1
(
    create_string datetime  ,
    username    varchar(32) );