my $fh = $c->req->upload('original')->fh;
$self->form->item->original($fh);
$self->form->item->update;
# The DBIx::Class row object comes from FormHandler,
# but thats not important here

##</code><code>##

my $fh = $c->req->upload('original')->fh;
binmode $fh;
my $img = Imager->new(fh => $fh)
  or die "Cannot read $fh ", $img->errstr;
my $medium = $img->scale(xpixels => 640, ypixels => 640, type => 'min');
my $thumb = $img->scale(xpixels => 200, ypixels => 200, type => 'min');
$self->form->item->medium_pfad($medium);
$self->form->item->thumb_pfad($thumb);
$self->form->item->original($fh);
$self->form->item->update;

##</code><code>##

$img->write(file => 'a.jpg');
$medium->write(file => 'b.jpg');
$thumb->write(file => 'c.jpg');
$fho = new IO::File "> a.jpg";
$fhm = new IO::File "> b.jpg";
$fht = new IO::File "> c.jpg";
# Then use these filehandles...