while (<DATA>) {
	s{(\d)\s+(\d)}{log(($1 * $2) || (1/2)) / log(2)}eg;
	print "New line: $_";
}

__DATA__
1 1 1 1 0 0 0 0 0 0 0 0
1 1 1 2 0 1 0 1 0 1 0 1
1 1 2 2 0 2 0 2 0 2 0 2
1 2 1 1 1 0 1 0 1 0 1 0
1 2 1 2 1 1 1 1 1 1 1 1
1 2 2 2 1 2 1 2 1 2 1 2
2 2 1 1 2 0 2 0 2 0 2 0
2 2 1 2 2 1 2 1 2 1 2 1
2 2 2 2 2 2 2 2 2 2 2 2