use strict;
use warnings;

while (<DATA>) {
    s/(?<!\d)0+(?=\d)//g;
    print;
}


__DATA__
010.231.000.049,41145,010.231.000.049,1363,CDU01V43
010.231.000.050,20,010.116.223.024,2803,ZVC629

##</code><code>##

10.231.0.49,41145,10.231.0.49,1363,CDU1V43
10.231.0.50,20,10.116.223.24,2803,ZVC629