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<datafield tag="650" ind1=" " ind2="2">
<subfield code="a">Toxicology.</subfield>
<subfield code="0">(OSt)1363</subfield>
</datafield>

<datafield tag="650" ind1=" " ind2="2">
<subfield code="a">Research work </subfield>
<subfield code="0">(OSt)1000</subfield>
</datafield>

my $twig = XML::Twig->new(
twig_handlers => { subfield => \&editSubfield, },
...
my $text = $href->text();
$href->set_text($rcnnew) if $text eq $rcnorig;
}

<?xml version="1.0" encoding="UTF-8"?>
<collection
...
</record>

</collection>