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use HTML::TableExtract;

...

try_match(\@headers1);
try_match(\@headers2);

<table class="gridtable" summary="RegTable">
    <tr>
...
        <td>Description</td>
    </tr>
</table>

$ perl 1092870.pl
TE here, headers: Address,Register,15,14,13,12,11,10,9,8,7,6,5
...
Address,Register,15,14,13,12,11,10,9,8,7,6
----------------------------------------------------------------------
+---------
$

attempt match on 15 ((?^mi:((9)|(8)|(7)|(6)|(5)|(15)|(14)|(13)|(12)|(1
+1)|(10)))): (15)
HPAT: /(?^mi:((9)|(8)|(7)|(6)|(15)|(14)|(13)|(12)|(11)|(10)))/
...
attempt match on 5 ((?^mi:((9)|(8)|(15)|(14)|(13)|(12)|(11)|(10)))): 0
attempt match on 4 ((?^mi:((9)|(8)|(15)|(14)|(13)|(12)|(11)|(10)))): 0
[...]

my @headers1 = (
    "Address",
...
    qr/^1$/,
    qr/^0$/,
);