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Gene exp1 exp2 exp3 exp4
1    a    b    c    d
...
4    m    n    o    p
5    q    r    s    t
6    u    v    w    x

Gene exp1 exp2 exp3 exp4
1    aa   bb   cc   dd
...
4    mm   nn   oo   pp
5    qq   rr   ss   tt
6    uu   vv   ww   xx

#! perl
use strict;
...
}

untie @array;

file1.dat,file2.dat
c,cc
...
o,oo
s,ss
w,ww