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use ExtUtils::MakeMaker;

...
    'VERSION_FROM'     => 'lib/Net/SSLeay.pm',
    'LIBS'             => ['-lssl -lcrypto -lcrypt32 -lz'],
);

use ExtUtils::MakeMaker;

...
    'INC'              => '-IC:/someplace/include',
    'LIBS'             => ['-LC:/someplace/lib -lssl -lcrypto -lcrypt3
+2 -lz'],
);