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# The while loop reads each line of the file, one at a time. You can
# then process each line individually.
...
    chomp( $_ );     # This removes the newline from each line.
    # Add code to process each URL.
}

open( INFO, $file );
# This will only read the file up to the first newline. If the lines
...
close( INFO );
chomp ( $line );
# Add code to process the first URL.

# Removes newlines from each array element at once.
chomp( @lines );