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                 Rate sExNibble singleNibble mExNibble  multi multiNib
+ble single
sExNibble      1795/s        --         -74%      -99%   -99%        -
+99%   -99%
...
multi        142315/s     7830%        1968%        6%     --        -
+46%   -58%
multiNibble  263146/s    14562%        3724%       95%    85%         
+ --   -22%
single       338640/s    18769%        4822%      151%   138%         
+29%     --

use strict;
use warnings;
...
    $string =~ s/\^s+//g;
    $string =~ s/\s+$//g;
}