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$some_content = 'so long Asian character (maybe it contain single quot
+ation)';
$sql = "insert into test_table(field) values ($dbh->quote($some_conten
+t))";
$dbh->do($sql); # you know, this works.

$some_content = $dbh->quote('so long Asia character (maybe it contain 
+single quotation)');
$sth = $dbh->prepare("insert into test_table(field) values (?)");
$sth->execute($some_content);
$sth->finish();