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INSERT member (last, first)
VALUES(NULL, "chromatic");

$last = "NULL";
$first = "chromatic";
$query = 
...
    VALUES ($last, $first)
};
$rows = $dbh->do($query);

$last = $dbh->quote("NULL");
$first = $dbh->quote("chromatic");

$query = 
qq {
    INSERT member (last, first)
    VALUES (?, ?)
};
$rows = $dbh->do($query, undef, $last, $first);