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  1. or download this
    my $NUM_THREADS = 5;
my $BUFFER_SIZE = 1;
...
}

$writerThr->join();
  2. or download this
    my $thr  = threads->create( sub {
    my $threadId = $i;
...

    close $REFERENCE_FILE;
} );#end sub
  3. or download this
    my $writerThr = threads->create( sub {
    my $numSeedsInv = 1.0 / $numSeeds;
...
    close $EXTENSION_FILE;
    close $UNMATCHED_FILE;
} );