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server old-ip-or-hostname-here prefer [burst iburst]

server new-ip-here prefer burst iburst  

 
server another-ip-or-hostname-here [burst iburst]

 
nothing (remove the line)

server 127.127.1.0

perl -p -i -e 's/server [\w\.]+ prefer.*/server new-ip-here prefer bur
+st iburst/g' ntp.conf