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$ tree -f -a .
.
|-- ./Foo
...
    `-- ./Foo-old/one.txt

3 directories, 4 files

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$ cat Foo-new.patch
diff -Npurd Foo-old/one.txt Foo-new/one.txt
...
@@ -0,0 +1 @@
+new file

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$ cd Foo

...
patching file one.txt
patching file two.txt

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$ patch -p0 -i../Foo-new.patch
can't find file to patch at input line 4
...

1 directory, 2 files

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diff -Npurd emptyDir tmpFoo  > tmpFoo.patch

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diff -Npurd emptyDir/Foo/one.txt tmpFoo/Foo/one.txt
--- emptyDir/Foo/one.txt    1969-12-31 16:00:00.000000000 -0800
+++ tmpFoo/Foo/one.txt    2012-08-16 08:21:35.609375000 -0700
...
@@ -0,0 +1 @@
+hi there

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$ cd tmp2Foo

...
`-- ./two.txt.rej

0 directories, 4 files

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$ patch -p1 -i ../tmpFoo.patch
patching file Foo/one.txt
...
    `-- ./Foo-old/one.txt

3 directories, 4 files

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$ patch -p0 -i ../tmpFoo.patch
patching file tmpFoo/Foo/one.txt
...
        `-- ./tmpFoo/Foo-old/one.txt

7 directories, 8 files

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$ patch -p0 -R -i ../tmpFoo.patch
patching file tmpFoo/Foo/one.txt
...
    `-- ./Foo-old/one.txt

3 directories, 4 files