Thanks. Using Module::Refresh directly fixed my issue.

$ cat class.pm                
package class;                                               
                                                             
use 5.014;                                                   
use strict;                                                  
use warnings;                                                
use autodie;                                                 
                                                             
sub new {bless {}, 'class'}                                  
                                                             
sub talk {print "6111513\n"}                                 
                                                             
1;                                                           
$ cat module_refresh_code.pl  
#!/usr/bin/env perl                                          
                                                             
use strict;                                                  
use warnings;                                                
use autodie;                                                 
                                                             
use 5.014;                                                   
use Data::Dumper;                                            
use Module::Refresh;                                         
                                                             
my $refresher = Module::Refresh->new;                        
                                                             
do './class.pm';                                             
                                                             
class->new->talk;                                            
                                                             
my $dummy = <>; # we change class.pm meanwhile               
                                                             
$refresher->refresh_module('./class.pm');                    
                                                             
class->new->talk;                                            
$ ./module_refresh_code.pl    
6111513                                                      
                                                             
8111513
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