I can see 2 problems. Your XML does not have an element named "href". You need to change elements named "subfield". Your regex is incorrect:

my $twig = XML::Twig->new(
    twig_handlers   => { subfield => \&editHref, },
    pretty_print    => 'indented',
);

$twig->parse($xml);
$twig->print;

sub editHref {
    my ( $twig, $href ) = @_;
    my $text = $href->text();
    my $orig = "(OSt)16";
    $text =~ s/\Q$orig/(OSt)20/;
    $href->set_text($text);
}
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Or, just avoid the regex...

sub editHref {
    my ( $twig, $href ) = @_;
    my $text = $href->text();
    $href->set_text('(OSt)20') if $text eq '(OSt)16';
}
[download]

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