G'day carlriz,

When you have problems installing any module, you should look for README and INSTALL files. These will generally tell about dependencies, prerequisites, and anything else important for installation.

Here's how to do it for DBD::mysql. (The process is much the same for any Perl module.)

1. Go to the CPAN documentation for your module. Near the top is a link to the distribution page which looks like "Module-Name-version.number". For the current version of DBD::mysql (at the time of writing) this is DBD-mysql-4.027. Follow this link.
2. On the distribution page, you'll find links to a variety of resources. In this instance, follow the README.pod link.
3. On the README page, you'll find a variety of information. In this instance, you'll see a link to DBD::mysql::INSTALL. Follow it.
4. Now you'll see lots of installation information. There's an answer to the question you've posed here. There's a Mac OS X section that will be important for you. There's a lot of other information which may be useful to you. I suggest you spend some time looking through this document.