Based on the other response, I installed the 32-bit Strawberry Perl and tried to install Win32::Serial module there. However, I still ran into an installation problem. As requested, I'm posting my error here.

C:\strawberry\perl\bin>perl -MCPAN -e "install Win32::SerialPort"
Database was generated on Fri, 02 May 2014 14:16:35 GMT

Running install for module 'Win32::SerialPort'
Running make for B/BB/BBIRTH/Win32-SerialPort-0.22.tar.gz
Fetching with LWP:
http://cpan.strawberryperl.com/authors/id/B/BB/BBIRTH/Win32-SerialPort-0.22.tar.gz
Fetching with LWP:
http://cpan.strawberryperl.com/authors/id/B/BB/BBIRTH/CHECKSUMS
Checksum for C:\strawberry\cpan\sources\authors\id\B\BB\BBIRTH\Win32-SerialPort-0.22.tar.gz ok

  CPAN.pm: Building B/BB/BBIRTH/Win32-SerialPort-0.22.tar.gz

found result=0, file=COM1
            Win32::SerialPort and Win32API::CommPort
                        VERSION 0.22

A 'Makefile' created for those with 'make' or CPAN.pm users.
It will test using PORT = COM1. To test using a different PORT,
run again specifying: 'perl Makefile.PL TESTPORT=<PORT>'
The normal 'Mantra' would then apply:
        make
        make test
        make install

For those without 'make' or an equivalent like 'nmake' or 'dmake' there
are perl-only scripts which do the same things:
        Test with:    perl nomake_test
        Install with: perl nomake_install

Test with nothing connected to COM1.
PORT is not verified present and accessible until tests run.
Timeout tests can take up to 30 seconds per test.

Creating new t/DefaultPort.pm
Creating new nomake_test
Creating new nomake_install
Checking if your kit is complete...
Looks good
Generating a dmake-style Makefile
Writing Makefile for Win32::SerialPort
Writing MYMETA.yml and MYMETA.json
cp lib/Win32API/CommPort.pm blib\lib\Win32API\CommPort.pm
cp lib/Win32/SerialPort.pm blib\lib\Win32\SerialPort.pm
  BBIRTH/Win32-SerialPort-0.22.tar.gz
  C:\strawberry\c\bin\dmake.exe -- OK
Running make test
C:\strawberry\perl\bin\perl.exe "-MExtUtils::Command::MM" "-MTest::Harness" "-e" "undef *Test::Harness::Switches; test_harness(0, 'blib\lib', 'blib\arch')" t/*.t
t/test1.t .. 224/309 can't get COMMPROP block at t/test1.t line 665.
can't get COMMPROP block at t/test1.t line 667.
can't get COMMPROP block at t/test1.t line 668.
can't get COMMPROP block at t/test1.t line 671.
can't get COMMPROP block at t/test1.t line 673.

#   Failed test 'except zero if quiet'
#   at t/test1.t line 673.
#          got: undef
#     expected: '0'
can't get COMMPROP block at t/test1.t line 674.
t/test1.t .. 305/309 # Looks like you failed 1 test of 309.
t/test1.t .. Dubious, test returned 1 (wstat 256, 0x100)
Failed 1/309 subtests
t/test2.t .. ok
t/test3.t .. 239/? can't get COMMPROP block at t/test3.t line 699.
can't get COMMPROP block at t/test3.t line 701.
can't get COMMPROP block at t/test3.t line 702.
can't get COMMPROP block at t/test3.t line 705.
can't get COMMPROP block at t/test3.t line 707.

#   Failed test 'quiet is one'
#   at t/test3.t line 707.
#          got: undef
#     expected: '0'
can't get COMMPROP block at t/test3.t line 708.
can't get COMMPROP block at t/test3.t line 711.
can't get COMMPROP block at t/test3.t line 714.
can't get COMMPROP block at t/test3.t line 715.
# Looks like you failed 1 test of 264.
t/test3.t .. Dubious, test returned 1 (wstat 256, 0x100)
Failed 1/264 subtests
t/test4.t .. ok
t/test5.t .. ok
t/test6.t .. 1/? SetCommState failed at t/test6.t line 306.
t/test6.t .. ok
t/test7.t .. ok

Test Summary Report
-------------------
t/test1.t (Wstat: 256 Tests: 309 Failed: 1)
  Failed test:  236
  Non-zero exit status: 1
t/test3.t (Wstat: 256 Tests: 264 Failed: 1)
  Failed test:  254
  Non-zero exit status: 1
Files=7, Tests=1808, 59 wallclock secs ( 0.31 usr +  0.03 sys =  0.34 CPU)
Result: FAIL
Failed 2/7 test programs. 2/1808 subtests failed.
dmake.exe:  Error code 255, while making 'test_dynamic'
  BBIRTH/Win32-SerialPort-0.22.tar.gz
  C:\strawberry\c\bin\dmake.exe test -- NOT OK
//hint// to see the cpan-testers results for installing this module, try:
  reports BBIRTH/Win32-SerialPort-0.22.tar.gz
Running make install
  make test had returned bad status, won't install without force
Stopping: 'install' failed for 'Win32::SerialPort'.