It is possible. There are a few things missing in your question, however: do you want to use Perl, or will a shell script suffice? are you logging onto the host using FTP, SSH, or Telnet?

Assuming that at this point you want only a proof that it can be done, here is a very, very basic example in shell.

 
#!/bin/bash
HOST=$1
ssh root@$HOST 'bash -s' <<'ENDSSH'
  # commands to run on remote host
  echo Installing httpd
  yum install -y httpd
  echo Yum exited with status $?
ENDSSH
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...and in Perl.

#!/usr/bin/perl
use v5.14;
use Net::SSH::Perl;

my ($host, $user, $pass) = @ARGV;

my $ssh = Net::SSH::Perl->new($host);
$ssh->login($user, $pass);
my($stdout, $stderr, $exit) = $ssh->cmd('ls -ltr');

say $stdout;
[download]

regards,
Luke Jefferson