MySQL has a "different" (not to say weird) way to quote quotes (hm, sounds funny, doesn;t it?). Anyways, it workslike this:

'The guy''s house' is "The guy's house" in perl (well, you could write
+ 'The guy\'s house', too..)
"He said ""Hello""" is "He said \"Hello\"" in perl (or, 'He said "Hell
+o"')
[download]

Knowing that you can use a very simple regexp to quote your comment:

#i assume here that you define $comment somewhere else..
$comment =~ s/"/""/g;       # if you use double-quotes
# OR: $comment =~ s/'/''/g; # is you use single-quotes
[download]

Hope this was of any help for you :)