I have a SSCCE, DebugR.cgi:

#!c:/Strawberry/Perl/bin/perl
use strict;
use warnings;
use Statistics::R;
use CGI qw(:standard escapeHTML -utf8);

print header(-type=>'text/html', -charset=>'utf-8');
my $R = Statistics::R->new();
print "R created\n";
$R->run('options(scipen = 999)');   #  disabling scientific notation i
+n R.
print "R initialised\n";
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Running this from the command line works as expected:

C:\Information\mgroot\cgi-bin>perl DebugR.cgi
Content-Type: text/html; charset=utf-8

R created
R initialised
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But pointing a browser to it via an Apache web server results in only the "R created" line and the following errors in the log:

[Wed Jan 29 13:58:44 2020] [error] [client 192.168.1.207] ack Invalid 
+argument: write( 5, 'cmd<-c("write(ngettext(1, \\"Error: \\", \\"\\",
+ domain=\\"R\\"), stdout())"); write("\\1",stdout())
[Wed Jan 29 13:58:44 2020] [error] [client 192.168.1.207] ' ) at C:/St
+rawberry/perl/vendor/lib/IPC/Run/IO.pm line 549.
[Wed Jan 29 13:58:44 2020] [error] [client 192.168.1.207] Warning: una
+ble to close filehandle GEN10 properly: Bad file descriptor during gl
+obal destruction.
[Wed Jan 29 13:58:44 2020] [error] [client 192.168.1.207] Warning: una
+ble to close filehandle GEN5 properly: Bad file descriptor during glo
+bal destruction.
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It is not obvious to me why there should be a difference or where to start looking next. Any clues would be appreciated.

Regards,

John Davies