try moving your From and To from header to sendmail() as per Email::Sender doc.

Trace begun at C:\Perl64\site\lib\Email\Sender\Simple.pm line 116

Also because line 116 from the latest Email::Sender::Simple, says:

  Email::Sender::Failure::Permanent->throw("no recipients") if ! @$to;
[download]

If all else fails, don't hesitate to edit the C:\Perl64\site\lib\Email\Sender\Simple.pm and add a few debug print statements, as the trace you got looks informatively useless to my untrained eye (edit: I meant to say, it's just a trace).

bw, bliako