G'day nysus,

The first thing that leapt out at me was:

Current perl:
Using system perl.
Shebang: #!/usr/bin/perl
[download]

That looks very wrong to me. One the main reasons for using perlbrew is that you avoid messing with the system perl.

I used to use perlbrew on macOS but haven't since about 2018/2019. I no longer have the Mac machine, so can't help with any direct testing. I do not recall output like that, but that's just a 4-5 year old memory.

I'm currently running perlbrew on Cygwin. I get:

$ perlbrew info
Current perl:
  Name: perl-5.34.0
  Path: /home/ken/perl5/perlbrew/perls/perl-5.34.0/bin/perl
...
[download]

What does `perlbrew info` output when run from the new (apparently, problem-free) account?

Did you accidentally `perlbrew switch` to the system perl on the old (problematic) account? If so, try switching to the last working perlbrew perl version and see if that helps.