Smart matching, introduced in Perl v5.10, was retroactively made experimental, with warnings as of v5.18. That means the operator may undergo significant changes or even be removed later! In general, if you want your code to be compatible across many versions of Perl, using regular loops, map or grep instead of its distributive property is better.

In this case, since in your example all the replacement parts of s/// are empty, the "looping over an array of regular expressions" technique is probably better. Also, unless the order of the substitutions you show in your example matters, maybe some of your regular expressions can be condensed (e.g. maybe s{[/?;.].*}{}?).