Yes, and you could have used it anyway if you called it by its full package name:

#!/usr/bin/env perl
use strict;
use warnings;
use 5.010;

require MIME::Base64;
my $x = MIME::Base64::encode_base64('abc');
say $x;
[download]

$ perl 1133493.pl
$ YWJj

$
[download]

Note the extra new line ... you will probably want to chomp what you get back from encode_base64 ....