Sure. I don't know what you've done to your script, but here's one which runs to completion and gives no such error message.

#!/usr/bin/env perl 
use strict;
use warnings;

use YAML qw/LoadFile/;

open my $fh, '<', '/dev/null';
my $config = LoadFile ($fh);
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Examine this code and compare it to your code. Start altering this code one line at a time to make it ever closer to your code, running it after each addition. If you hit a problem you will then know precisely which change caused the problem.