I don't know how to do this, but some of the following links look promising

Blat at http://gepasi.dbs.aber.ac.uk/softw/Blat.html

Discussion of Perl on Windows http://www.pconline.com/~erc/perlwin.htm

Rather undiscriminating list of e-mail programs http://cgi.resourceindex.com/Programs_and_Scripts/Perl/Web_Based_E_Mail/

Useful list of links for e-mail on WinNt http://www.geocities.com/SiliconValley/Park/8312/mail.htm

-- Anthony Staines