Dear community, thank you all to partecipate, I would like to share my (very simply) solution to my question. The following code works perfect and suit my needs.

BTW, the concept behind solution is simple too:
-- Open a socket
-- Server is listining?
---- YES: OK Connect
---- NO: Enter in loop until Server will be ready
-- Send data
-- Is there any response from server?
---- YES: Continue sending loop
---- NO: (Empty Response): Call OpenSocket and wait untill Server will be ready again.

#!/usr/bin/perl
use IO::Socket;
my $sock1;
sub OpenSocket{
  while ( !$sock1 ) {
    $sock1 = IO::Socket::INET->new (
             Proto            => "tcp",
             PeerAddr    => "192.168.10.7",
             PeerPort        => "8000",
             Timeout        => "1")
  }
}

################ START SCRIPT #################

OpenSocket();
sleep(1);
my $str="DATA TO SEND"
while(1) {
  $sock1->send($str);
  sleep(1);
  $sock1->recv($channel1, 128);

  if ( !$channel1 ) {
    $sock1->shutdown(2);
    $sock1="";
    print "DISCONNECTED... I'M RECONNECTING AND RESEND PREVIOUS PACKET
+\n";
    OpenSocket();
    sleep(1);
    $sock1->send($str);
 }
}
close($sock1);
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